Hold on, hold on. :roll:
Many bikes over the years are wet over powder- Fats and Salsas are two of many. Wet paint will stick to powder with no primer required but does need carefull prep.
First off make sure the frame is spotless. That means everywhere, especially around BB and headset if it has been built up since powder. This can be done firstly with hot soapy water and then ideally with pre-paint (some good motor shops have it).
Then you need to key the surface. 600 grit wet and dry is ideal. Make sure you get into all the nooks and crannies.
Now you can continue as a regular repaint, dry, degrease, tack, paint etc.
It is an absolute myth that paint doesn't stick to powder- i have been painting over powder for 20 years and have yet to have a problem when correct prep has been done.
Si